Figure 8-1 shows the general xanthine structure and the structures of theophylline (1,3-dimethylxanthine) and caffeine (1,3,7-trimethylxanthine). Citation. Monitor therapeutic effectiveness which is indicated by relief from pain and cramping in calf muscles, buttocks, thighs, and feet during exercise and improves walking performance (time and duration). Methylxanthines -inhibits phosphodiesterase leads to incr. Methylxanthines are bronchodilators used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). It is recommended that caffeine be discontinued for at least 24 hours prior to stress testing. METHYLXANTHINES NURSING IMPLICATIONS? Less frequent nocturnal asthma. Assessment & Drug Effects. Therefore, a calm approach is an important aspect of care. Describe the therapeutic serum or plasma theophylline level and the toxic level. cAMP so bronchodilation -decr. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Contrast the therapeutic effects of leukotriene antagonists, glucocorticoids, cromolyn, antihistamines, and mucolytics for COPD and asthma. Nursing Implications. METHYLXANTHINES PATIENT TEACHING? Monitor BP if patient is also on antihypertensive treatment. Methylxanthines; Nursing Management. Methylxanthines (nursing considerations: • Advise clients to avoid consuming caffeinated beverages (coffee, caffeinated colas). Start studying MCC nursing 1355. Narrow margin of safety & high risk of toxicity - SX: anorexia, N/V, restlessness, insomnia, seizures, dysrhythmias. Because of their methyl attachments, these agents are often referred to as methylxanthines. Although nursing considerations and implications are slightly different, most nursing resources and textbooks use them interchangeably. Describe the side effects of beta 2-adrenergic agonists and methylxanthines. Specific xanthine agents. The patient and family are often frightened and anxious because of the patient’s dyspnea. The immediate nursing care of patients with asthma depends on the severity of symptoms. Please consult the latest official manual style if you have any questions regarding the format accuracy. Reginald P. Sequeira, in Side Effects of Drugs Annual, 2009. • Phenobarbital and phenytoin decrease theophylline levels. histamine release -stimulates ciliary transport of ... Drug Mechanism Use Side/Adverse Effects Nursing Implications Cromolyn Sodium (non-steroidal) INTAL -prevents influx of Ca into mast cells, therefore inhibiting degranulation and release of Find patient medical information for Duoneb Inhalation on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Caffeine: (Major) Methylxanthines, through antagonism of adenosine and thus pharmacologic-induced coronary vasodilation, have been associated with false-negative results during dipyridamole-thallium 201 stress testing. 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